The asthma

Asthma is a potentially serious condition. If it is not treated in the day day, risks of severe attacks greatly increase. Asthma drugs are numerous and varied. Doctissimo made the point on the different classes used, their role and their mode of action.

Asthma is a chronic disease characterized by episodes of breathing difficulty. It is due to problems at the level of the bronchi:


-A hyper-reactivity;
-Local inflammation;
-A decrease in diameter = bronchoconstriction.
Treatment of asthma is therefore designed to combat these disorders. To combat the hyper-reactivity and local inflammation bronchial, anti-inflammatory drugs and allergy are drugs of choice. For bronchoconstriction, of drugs to dilate the bronchial tubes will be effective: bronchodilators.

Anti-asthma medication, intended to take action on the bronchial tubes will be so administered often inhaled route. However, the oral will be usable just as the injection, including emergency.Treatment of asthma has two slopes because it is necessary to deal with crises when it occur but also the asthma field by substantive processing.

Background processing
Background processing is especially designed to reduce local inflammation and the hyperresponsiveness. It is mainly based on daily intake of inhaled steroids, Inhaled cromones orantileukotrienes. Taking an antihistamine will also act on allergic asthma field.

It is also interesting to reduce respiratory discomfort by using a bronchodilators.Of anticholinergics inhaled are bronchodilators by a local anticholinergic effect at the level of the bronchial musculature. Bronchodilators stimulating beta2 to long duration of action, inhaled or oral are sometimes associated with anti-inflammatory but never given treatment only.

There are also formulations combining an inhaled corticosteroid and bronchodilator stimulant of long acting beta2 for substantive treatment of persistent asthma. Only the doctor can decide what treatment is adapted to each case. Theophylline is the oldest bronchodilator.

It is less used because it presents side effects (gastrointestinal, cardiac and neurological) and a low therapeutic margin. In short, it is difficult to adjust the dosage to have an effective treatment without the risk of toxicity.