For treating pediatric cancers, girls receive a chest radiotherapy. Essential element of support, this technique exposed however to an increased risk of developing breast cancer later. This driving would be comparable to that of women with genetic predispositions to disease. The results of this study presented to the US Congress of cancer advocates early screening.
Women who received radiation therapy to treat cancer in childhood should be screened for early breast cancer. Radiation therapy remains an essential element of support of many pediatric cancers. But this technique can increase the risk of developing breast cancer chest exposure. But in what proportion? Out the1 study presented at the American Congress on cancer ASCO 2012 sought to compare this risk to that related to genetic predispositions. We analyzed the data over 1 200 women who had chest radiation therapy to treat pediatric cancer. The risk associated with genetic predispositions (genes BRCA1/BRCA2 alterations) was evaluated on the study WECARE including 4 570 women with a relative of first degree of breast cancer and who was in life a year after diagnosis.
For those having a pediatric cancer, close to a woman aged 50 years on 4 (24%) had breast cancer. Among those treated for Hodgkin’s lymphoma, the disease was almost one woman in three (30%), a risk the same as women with genetic predisposition BRCA1 (31%) – the risk associated with BRCA2 is estimated at 10%. In comparison, the risk to the general population of women 50 years of age is 4%. Continue reading “The Health News”