Drug of the 1990s, Prozac ® has been dubbed “happy pill”. It is true that as antidepressant treatment is today one of the most prescribed in the world. Leader of a new class of antidepressants, Prozac ® has a great success with French practitioners. But it is now competed by other more recent molecules.

Until the beginning of the 1990s, the depressed had certainly effective antidepressants, but they were relatively difficult to manipulate and sometimes the origin of side effects.

Depression after Prozac

Prozac General practitioners were reluctant so to support them depressed and willingly spent hand psychiatrists. Everything changed with the arrival of Prozac®. Well tolerated, supported by a very active commercial policy, this drug was quickly very prescribed, a success which also explains that consumption has been deemed excessive by some experts as Pr Edouard Zarifian.

Certain antidepressant

Prozac ® consists of fluoxetine, a substance that has the particularity to inhibit reuptake of serotonin, a brain neurotransmitter almost exclusively. It thus increases the concentration of serotonin neurons. However it has been shown that depressive patients had a lesser concentration of degradation products of serotonin in the cerebrospinal fluid (surrounding the brain). Many medical studies have demonstrated that fluoxetine reduces depressive symptoms and also reduces the intensity of other mental disorders, obsessive compulsive disorders.

As other antidepressants, Prozac ® helps reduce feelings of sadness and deduction, that characterize the depressed, the condition to wait a few weeks of treatment and continue this for long enough, generally 6 months. But, more than its effectiveness that seems in fact a little lower than that of previous generations of antidepressants, it is his job security that is interesting. Because it does not change or little other brain mediators such as acetylcholine, Prozac ® does indeed not dryness of the mouth, prostate problems and lower blood pressure.

In addition, it is low toxicity, especially for the heart, which allows to give heart, older patients or taking many drugs. In the depressed, in which the risk of suicide is always present, this is also a reassuring element.

A few precautions however

However, outside its effectiveness which is sometimes insufficient in severe depression, Prozac ® exposes a few disadvantages. Thus, sometimes, that its administration induces a certain nervousness or insomnia in patients, or even an episode of over-stimulation. Conversely, it can cause drowsiness, an effect which should be drivers of motor vehicles. Small digestive problems (nausea, constipation) and skin rashes have been reported. Finally, Prozac ® requires a few precautions people sick of the liver, diabetic, epileptic or receiving oral anticoagulants.

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Drug of the 1990s, Prozac ® has been dubbed 'happy pill'. It is true that as antidepressant treatment is today one of the most prescribed in the world. Leader of a new class of antidepressants, Prozac ® has a great success with French practitioners. But it is now competed...