COLORECTAL CANCER AND GENETIC PREDISPOSITION

The screening program for colorectal cancer is for all people aged over 50 years. Diagnosed early, it can be cured in more than 9 out of 10. However, there are cases of inheriting the cancer colorectal requiring special care including a consultation with a geneticist.

1.The high incidence of colorectal cancer
2.Aggravating factors and protective for colorectal cancer
3.Genetic predisposition for colorectal cancer
4.The colorectal cancer screening

COLORECTAL

When colorectal cancer is detected early, the chances of recovery above 90%. Mass screening using the Hem occult II ®, now organized throughout the country, to identify early colorectal cancer and thus significantly improve the prognosis of the patient. Operation “Blue March” aims to further sensitize the population on this screening too little follow-up since the national participation rate over the period 2009-2010 is 34% (1).

The high incidence of colorectal cancer

Colorectal the cancer is the third most common cancer in the French population after prostate cancer and breast cancer. In France about 40,000 new cases are diagnosed annually, with an average age of diagnosis greater than 65 years . Very common and often diagnosed at a stage advanced (almost half of cases), this cancer is often severe and only 1 patient heals 2, 5 years after diagnosis. This observation makes it the second leading cause of cancer death in France with 17,400 estimated deaths per year, being the leading cause of lung cancer .

Aggravating factors and protective for colorectal cancer

The risk of developing colorectal cancer may be increased by various environmental factors of daily life such as obesity, excessive consumption of red meat and processed meats, tobacco, alcohol, but also because of genetic factors called genes of predisposition (or susceptibility). Conversely, protective factors tend to reduce the risk of developing cancer colorectal l such that regular physical activity, a diet rich in fiber and calcium, dietary supplement vitamin D, and also the regular intake of low-dose aspirin (attention, taking aspirin is not harmless, medical advice is absolutely necessary and self-medication is not recommended