Lung Cancer: for better prevention

If the smoking cessation reduces the risk of lung cancer, we know that former smokers are still most at risk. Researchers have found a way to restore balance. But for those who continue to smoke during treatment, continue to reduce their chances of healing…

Lung Cancer

The best prevention against cancer of the lung is undoubtedly not smoking or to stop. Despite a successful cessation, the damage inflicted by tobacco make the former smoker a person more at risk than non-smokers. This is why researchers explore many avenues to prevent disease.

A derivative of vitamin A in the prevention
Researchers1 attempted to evaluate the preventive effect of two forms of vitamin A (9 – cis retinoic acid) or 13 – cis retinoic acid. In total, 266 ex-smokers long term having stopped for at least one year were selected at random to receive either one of the two forms of Retinoic acid or a placebo.

Retinoic acid plays an important role in the development of the lungs of the embryo, by acting on the control of proliferation and differentiation of cells of lung tissue. Then (after birth), it activates certain genes involved in the fight against cancer. Now we know that strong habits can induce reductions in concentration of Retinoic acid, resulting in an increase of precancerous changes.

After three months of follow-up, fewer of this type were observed in the lungs of patients receiving 9 – cis retinoic acid, compared to the two other groups. More more work are needed before we can recommend this compound in prevention, but these early results were deemed encouraging by the authors.

Smoking during the reduced salary rate survival
This isn’t a surprise: people with small cell lung cancer have every interest in quitting during their treatment. If common sense is not enough to decide, this is a new2 study which should definitely make them quit.